Jane's World is a fun adventure for the reader. There is lots of humor that ranges from laugh out loud to absurd.
The characters, who I was generally unfamiliar with as I have only read a little bit of the comic, are a unique group. At least, that is the best description I have for them. They are characters (here meaning "interesting or amusing individuals").
The plot is illogical at best, but it sort of adds to the fun of the book. Jane is struggling because Dorothy broke up with her (again). Dorothy loves Jane and is upset with herself for letting Jane go. And then Jane gets a call from Ethan, her roommate, saying she needs to come home right now. So Jane makes excuses at library (her employer) to go home, only to find out she's "engaged" to a mail order bride named Natasha. The story spirals from there.
In general, Jane's World is a lighthearted book. And rather enjoyable to read in an incredulous sort of way.