A laugh-out-loud, bittersweet debut full of wit, wisdom, heart, and a hilarious, unforgettable heroine.

When you're a hypochondriac, there are a million different things that could be wrong with you, but for Izzy, focusing on what could be wrong might be keeping her from dealing with what's really wrong.

I almost raised my hand, but what would I say? "Mr. Bayer, may I please be excused? I'm not totally positive, but I think I might have cancer." No way. Then everyone at school would know, and they would treat me differently, and I would be known as "Izzy, that poor girl who diagnosed herself with breast cancer during biology."

But Izzy's sense of humor can only get her so far when suddenly her best friend appears to have undergone a personality transplant, her mother's health takes a turn for the worse, and her beautiful maybe-boyfriend is going all hot and cold. Izzy thinks she's preparing for the worst-case scenario, but when the worst-case scenario actually hits, it's a different story altogether--and there's no tidy list of symptoms to help her through the insanity.