CRISPR People

The Science and Ethics of Editing Humans

by Henry T. Greely

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Pub Date Feb 16 2021 | Archive Date Feb 25 2021

MIT Press | The MIT Press

Science

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Description

What does the birth of babies whose embryos had gone through genome editing mean--for science and for all of us?

In November 2018, the world was shocked to learn that two babies had been born in China with DNA edited while they were embryos--as dramatic a development in genetics as the cloning of Dolly the sheep was in 1996. In this book, Hank Greely, a leading authority on law and genetics, tells the fascinating story of this human experiment and its consequences. Greely explains what Chinese scientist He Jiankui did, how he did it, and how the public and other scientists learned about and reacted to this unprecedented genetic intervention.

Advance Praise

“America's most quoted bioethicist has written the definitive guide to the international consensus against germline editing... and how it all came crashing down in November 2018. In a concise retelling that's part diary, part history, and part journalism, Hank Greely pieces together how a Chinese scientist defied bioethics—and common sense—to create the first gene-edited humans."

Antonio Regaladobiomedicine editor, MIT Technology Review

“Hank Greely is a master of detail, and delivers an 'as if you were there' portrayal of events surrounding the announcement of the first children born with edited genomes. For anyone who wants to know how we got there, and where we go next, this is the book for you. With both nuance and wit, Greely makes you an expert, too."

R. Alta CharoWarren P. Knowles Professor of Law, University of Wisconsin–Madison

“Hank Greely, a renowned authority on science and law, delves deeply into the complex, evolving world of human germline genome editing, offering a story rich in scientific fact, but also a fascinating portrayal of key players, critical turning points, and the promise and peril of this scientific advance."

Margaret HamburgFormer FDA Commissioner

“America's most quoted bioethicist has written the definitive guide to the international consensus against germline editing... and how it all came crashing down in November 2018. In a concise...