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Throughout history, humans have contended with pandemics. History is replete with references to plagues, pestilence, and contagion, but the devastation wrought by pandemics had been largely forgotten by the twenty-first century. Now, the enormous human and economic toll of the rapidly spreading COVID-19 disease offers a vivid reminder that infectious disease pandemics are one of the greatest existential threats to humanity. This book provides an accessible explanation of how viruses emerge to cause pandemics, how our immune system combats them, and how diagnostic tests, vaccines, and antiviral therapies work-- concepts that are a foundation for our public health policies.
This remarkable book will take the reader on a fascinating journey—how scientists have developed a deep understanding of our immune system, how this system fights viruses, and how vaccines and antiviral therapies work. This human story addresses the many questions that people worldwide are grappling with during the current global pandemic.
Arun MajumdarStanford University and Founding Director of ARPA-E
Chakraborty and Shaw's book will satisfy the public thirst for an authoritative account of how destructive pandemics survive despite enormous growth in scientific understanding. Their sobering view of the challenges that remain—to understand antibody action and develop effective vaccines—deserves close attention.
John DeutchFormer Provost Institute Professor Emeritus, MIT
The authors provide a readily accessible introduction to viruses, a class of tiny human pathogens with surprising potential to cause transmissible, sometimes fatal, disease. They speak from a deep understanding of the viruses and the body's response to viral infections. A great book for people who want to understand why viruses are such a challenge to human life.
David BaltimoreProfessor, California Institute of Technology, 1975 Nobel Prize in Medicine for work in virology
This is a wonderful book that beautifully explains, in a very easy-to-read and understandable way, the history of pandemics and how the diseases that cause them may be conquered.
Robert LangerInstitute Professor, MIT, and recipient of the US National Medal of Science and the US National Medal of Technology and Innovation