Trissel’s Stability of Compounded Formulations, 5th Edition

Trissel’s Stability of Compounded Formulations*** is the only book in print that provides a single compilation of all currently available stability information on drugs in compounded oral, enteral, topical, ophthalmic, and other specialized preparations. Based on data published over the past 55 years, the reference summarizes specific formulations and stability studies. The framework of this book will help readers determine whether formulated compounds will be stable for the anticipated duration of use, properly store and repackage compounded formulations, formulate in accordance with documented standards, and counsel patients on the use and storage of compounded medications.

Key Features
• The new edition includes completely updated monographs on 510 products—an increase of 77 compared with the 4th edition—are arranged alphabetically by nonproprietary name.
• Each monograph is organized into three easy-to-use categories: Properties, General Stability Considerations, and Stability Reports of Compounded Preparations.
• Additional categories—Compatibility with Other Drug Products and Compatibility with Common Beverages and Foods—that are included when information is available.
• 1,714 references—481 new to the 5th edition—are from worldwide literature spanning the past 55 years.
• Two appendices—Beyond-Use Dating for Nonsterile Compounded Preparations and Beyond-Use Dating for Sterile Compounded Preparations—provide a summary of United States Pharacopeia benchmarks for assigning beyond-use periods in the absence of relevant research.
• Index of nonproprietary and brand names is provided.

Table of Contents
• Preface
• Monographs
• Appendix I: Beyond-Use Dating for Compounded Nonsterile Preparations
• Appendix II: Beyond-Use Dating for Compounded Sterile Preparations
• References
• Index

***The lidocaine hydrochloride concentration listed in two places as 40 mg/L is incorrect. It should read 40 mg/mL. The error appears on page 188, third line of Study 1; and on page 289, fourth line under the Topical heading. The errors will be corrected in a forthcoming reprint of the book.