Dr. Brett Carson, Epidemic Intelligence Service agent for the Centers for Disease Control, just back from five months in the Arctic, is hurriedly sent to Guatemala to investigate the source of a mysterious and deadly Ebola-like virus that is sweeping through jungle villages.

Brett soon meets the beautiful Kari Wheeler, daughter of an anthropologist who is searching the area for ancient Mayan tombs and artifacts. 

Civil war, tomb raiders, a rescue dog, a bullet-riddled Jeep, and an outbreak of the disease at an isolated New Mexico monastery lead Brett and Kari on a perilous chase to identify and stop the spread of the virus—and well as save their own lives from relentless killers who are closing in on their trail.