Radclyffe, a retired surgeon and full time author-publisher, has published over fifty novels as well as dozens of short stories, has edited numerous anthologies, and, writing as L. L. Raand, has authored a paranormal romance series, The Midnight Hunters.

She is a seven time Lambda Literary Award finalist in romance, mystery and erotica--winning in both romance (Distant Shores, Silent Thunder) and erotica (Erotic Interludes 2: Stolen Moments edited with Stacia Seaman and In Deep Waters 2: Cruising the Strip written with Karin Kallmaker). A member of the Saints and Sinners Literary Hall of Fame, she is also a 2010 RWA/FF&P Prism Award Winner for Secrets in the Stone, an Independent Publisher's award winner (IPPY), an Alice B. Readers' award Winner, and a finalist for the Benjamin Franklin award, the ForeWord Review Book of the Year award, and the 2010 Heart of Excellence Readers' Choice award.

She is also the president of Bold Strokes Books, one of the world’s largest independent LGBT publishing companies.