The Nocebo Effect

When Words Make You Sick

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Pub Date Mar 19 2024 | Archive Date Dec 12 2023

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Description

An investigation of the nocebo effect—the placebo effect's evil twin.

Can beliefs make you sick? Consider "The June Bug" incident from a US textile factory in the early 1960s.  Many employees began to feel dizzy, had an upset stomach, and vomited. Some were even hospitalized. The illness was attributed to a mysterious bug biting workers. However, when the CDC investigated this outbreak, no bugs or any other cause of the illnesses could be identified. Instead, it appears to be an illness caused by the mind -- that is, sickness due to expectation.

The June Bug story is one of many striking examples of the nocebo effect, a phenomenon best summarized as the occurrence of a harmful event that stems from expecting it. The nocebo effect plays a role in side effects for some of the most commonly prescribed medications. It provides a lens for understanding how sensationalized media reports that sound alarm about public health might even become a self-fulfilling prophecy. It might even explain the mysterious symptoms associated with Havana Syndrome, during which dozens of US government employees fell ill after reportedly being exposed to an unidentified sound wave in Cuba.

We are just discovering the power behind this effect and how it can be ethically mitigated. Enlightening and startling, The Nocebo Effect is the first book dedicated to investigating this fascinating phenomenon by the foremost experts in the field.

An investigation of the nocebo effect—the placebo effect's evil twin.

Can beliefs make you sick? Consider "The June Bug" incident from a US textile factory in the early 1960s. Many employees...


Advance Praise

"In this pioneering book, leading researchers show how words help shape our conscious experience of the world, which in turn directly affects our bodies and our health. The more we know, the more we can say ‘no’ to nocebos.” – John Bargh, Susan Nolen-Hoeksema Professor of Psychology and Cognitive Science, Yale University, and author of Before You Know It: The Unconscious Reasons We Do What We Do

“An excellent and well-written discussion of ‘the pla­cebo effect’s evil twin’ by leading researchers in the field. Reading this book has the potential of decreasing the reader’s experience of nocebo effects, and for that reason, I highly recommend that it be read by everyone.”—Irving Kirsch, Associate Director of the Program in Placebo Studies at the Harvard Medical School and author of The Emperor’s New Drugs

“An outstanding compilation of the latest research by eminent researchers in the field. Written in an understandable way, The Nocebo Effect is a helpful manual for readers to stop “nocebo-ing” themselves.”—Jeremy Howick, Director of the Stoneygate Centre for Empathic Healthcare at the University of Leicester, Director of the Oxford Empathy Program, and author of The Powerful Placebo

“A fascinating multidisciplinary volume that offers a comprehensive understanding of an underappreciated force in medicine and psychology, and provides illuminating insights into improving care.”—Rob Henderson, founding faculty fellow at UATX and author of Troubled: A Memoir of Foster Care, Family, and Social Class

"The nocebo effect has been so far understudied and underestimated compared to the placebo effect. This volume fills that gap by providing an exciting, comprehensive, and interdisciplinary account of a phenomenon that certainly needs more attention."—Fabrizio Benedetti, M.D., Professor of Neurophysiology, University of Turin Medical School, Turin, Italy

“This book is needed, comprehensive, evidence-based and, most importantly, opens as many discussions as it provides answers. A must-have and must-read for anyone in clinical practice and research.”—Prof. Dr. Jens Gaab, University of Basel, Switzerland

"In this pioneering book, leading researchers show how words help shape our conscious experience of the world, which in turn directly affects our bodies and our health. The more we know, the more we...


Available Editions

EDITION Other Format
ISBN 9798887700243
PRICE $26.99 (USD)
PAGES 256

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Featured Reviews

Thank you to NetGalley and Mayo Clinic Press for this eARC.

I was really looking forward to this read, thinking it would be interesting. And while there were some interesting points, for the most part it was disappointing. Each chapter was written by a different person and there was a lot of variation in writing style which made some chapters more engaging than others, but made the book as a whole feel disjointed. There was also a lot of repetition, perhaps also due to the chapters being written by different people. Overall, the book was well researched but for me lacked the specific scientific (in particular physiological and biochemical) information I was expecting (and wanting). Furthermore, a lot of the conclusions were opinions and essentially common sense.

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