Lorelei, a 60-year-old virgin, owns a Miami lingerie shop, eats organic food, and minds her own business. She never considers alternatives to this life until the day her well runs dry, when Juan the well-digger plunges its depths and taps into the flow of hidden water from an underground spring. She attributes her awakening sensuality and increasingly youthful appearance to her healthy lifestyle. Her business partner, Sharleen, suspects that the water has more to do with Lorelei's changes than the ingestion of kale and quinoa, and embarks on a campaign to sell it from the shop.

Someone else is interested in this water: Winona, a 500-year-old Native American woman who has been following the spring through the ages in her eternal search for youth, and has lost its trail. She finds it in Lorelei's back yard, and is desperate to claim it once again for herself. Her obsession leads to Juan's linked ancestry to Ponce de Leon, to Winona's connection with that history, and to the ultimate convergence of all their stories. Obsession with youth, fear of death, and the vagaries of time are ideas explored by quirky characters with depth and insight beneath their offbeat humor.