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Blood Poison

The Untold Story of Sepsis

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Pub Date Jul 14 2026 | Archive Date Not set

Amplify Publishing Group | Amplify Publishing


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Description

A frontline doctor’s sweeping, deeply researched, and intimately written chronicle of the centuries-long effort to understand and effectively treat sepsis—one of history’s most lethal, misunderstood maladies and the leading cause of death for children worldwide.

When presented with a patient with a severe infection, there is one question that everyone must ask themselves: Could it be sepsis?

Since the earliest days of medicine, sepsis has been one of its most confounding and dangerous conditions—first emerging in its modern understanding from the trenches of pre-antibiotic battlefields as “blood poisoning” (aka septicemia) but evolving to be understood as an elusive syndrome in which the body’s immune response spirals out of control with immediate and deadly consequences.

In the tradition of sweeping medical narratives like The Emperor of All Maladies and The Great Influenza, Blood Poison traces the history of sepsis from its origins in ancient civilization in the poetry of Homer and the theories of Hippocrates to its establishment in the modern age as the scourge of emergency rooms and hospital wards that is responsible for one in five deaths each year around the world.

With riveting patient stories, insights from top experts, and moving firsthand accounts of his work as a doctor, advocate, and a leader in the field, Parsa Shahinpoor brings readers inside the fight to raise awareness about new and effective ways to fight an insidious illness, which—due to the rise of drug-resistant superbugs, viral pandemics, and an ailing healthcare system—is only getting more dangerous.

A frontline doctor’s sweeping, deeply researched, and intimately written chronicle of the centuries-long effort to understand and effectively treat sepsis—one of history’s most lethal, misunderstood...


Advance Praise

“Shahinpoor tells the story of sepsis—from earliest mention in Greek poetry to contemporary management and policy efforts. Through vivid storytelling, he brings to life the patients, families, clinicians, scientists, and policymakers who have shaped our current understanding. Blood Poison is a must-read for the many people whose lives have been touched by sepsis.”

—Hallie Prescott, MD, co-chair, Surviving Sepsis Campaign Guidelines Committee, and International Sepsis Forum council member 

 

“What a great read! Although I’ve spent a long time studying sepsis, even I learned a great deal from this amazingly thorough exploration of one of medicine’s most ancient and misunderstood maladies. He does a terrific job both of tracing the history and science behind this mysterious syndrome and placing it in a very immediate and intimately human context.”

—Derek C. Angus, MD, MPH, chair, Department of Critical Care Medicine at UPMC, and senior editor, JAMA 

 

Blood Poison is a powerful and timely account of sepsis—clear, compelling, and grounded in both science and humanity. A must-read for anyone committed to understanding and combating this global health threat.” 

—W. Joost Wiersinga, MD, PhD, MBA, professor of medicine and chair, Division of Infectious Diseases at the Center for Infection and Molecular Medicine (CIMM)

 

“Dr. Shahinpoor provides an impressive summary of the current understanding of the sepsis syndrome. All health care professionals can benefit from this book. 

—David Gilbert, past president, Infectious Diseases Society of America, and recipient of the IDSA Alexander Fleming Award for Lifetime Achievement

“Shahinpoor tells the story of sepsis—from earliest mention in Greek poetry to contemporary management and policy efforts. Through vivid storytelling, he brings to life the patients, families...


Available Editions

EDITION Hardcover
ISBN 9798891387164
PRICE $32.00 (USD)
PAGES 440

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